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This page gives details of CPPsite entry with ID 2008
Primary information
CPPsite ID2008
PEPTIDE SEQUENCERWRWRWRW
PEPTIDE NAME(RW)4
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONNucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
CHEMICAL MODIFICATIONDrug conjugated with peptide through linker
UPTAKE EFFICIENCYLow comapred to cyclic [W(RW)4]
INVITRO/INVIVOIn vitro
CELL LINEMDA-MB-468, HCT-116, CCRF-CEM, and SK-OV-3
CARGOSmall molecule drug (Doxorubicin)
PMID23301519
PATENTUnknown
LENGTH8
Secondary StructureCCCCCSCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)