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This page gives details of CPPsite entry with ID 2038
Primary information
CPPsite ID2038
PEPTIDE SEQUENCEAGYLLGKINLKALAALAKKIL
PEPTIDE NAMENF61
CHIRALITYModified
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYAmphipathic
N-TERMINAL MODIFICATIONStearylation
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONα-NH2 group of Lys7 for subsequent synthesis
UPTAKE EFFICIENCY10-100 fold higher than stearyl-TP11
INVITRO/INVIVOin vitro
CELL LINE
CARGONucleic acid (Plasmid DNA, SCO and siRNA)
PMID23357356
PATENTUnknown
LENGTH21
Secondary StructureCCCCCTTSCTHHHHHHHTTTC
SMILESN[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C=O
Tertiary Structure
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  (PEPstrMOD)