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This page gives details of CPPsite entry with ID 2049
Primary information
CPPsite ID2049
PEPTIDE SEQUENCERPARPAR
PEPTIDE NAMEPA 5
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONVesicles
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYSimilar for RPARPAR PAs with amidated C-terminus
PROPOSED UPTAKE MECHANISMClathrin- independent Carriers (CLIC) pathway
INVITRO/INVIVOIn vitro
CELL LINEPPC-1 and M21
CARGODSP-PEG2000 and Fluorophore (Rhodamine)
PMID23349939
PATENTUnknown
LENGTH7
Secondary StructureCCSSTTC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)