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This page gives details of CPPsite entry with ID 2069
Primary information
CPPsite ID2069
PEPTIDE SEQUENCECVSRRRRRRGGRRRR
PEPTIDE NAMELMWP
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
PROPOSED UPTAKE MECHANISMClathrin-mediated and cytoskeleton-dependent endocytosis as well as energy independent internalization
INVITRO/INVIVOIn vitro and in vivo
CELL LINEHT-1080 and brain capillary endothelial cell bEnd.3 cell line
In VIVO MODELAdult male BALB/c nude mice and male SpragueDawley rats
CARGONanoparticles and Fluoriophore (coumarin-6)
PMID23350619
PATENTUnknown
LENGTH15
Secondary StructureCCCHHHHCCCSCCCC
SMILESN[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)CO
Tertiary Structure
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  (PEPstrMOD)