This page gives details of CPPsite entry with ID 2122 |
Primary information | |
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CPPsite ID | 2122 |
PEPTIDE SEQUENCE | AGYLLGHINLHHLAHLHHILC |
PEPTIDE NAME | TH peptide |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Cytosol, ER and Golgi body |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | High |
PROPOSED UPTAKE MECHANISM | Electrostatic attraction and clathrin-mediated endocytosis |
INVITRO/INVIVO | In vitro and in vivo |
CELL LINE | C26 cells and HepG2 cells |
In VIVO MODEL | BALB/C mice |
CARGO | Nanoparticle (Liposomes) |
PMID | 23891517 |
PATENT | Unknown |
LENGTH | 21 |
Secondary Structure | CCSSCCCCSHHHHHHHTSTTC |
SMILES | N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |