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This page gives details of CPPsite entry with ID 2124
Primary information
CPPsite ID2124
PEPTIDE SEQUENCEAGYLLGKINLKKLAKLLLIL
PEPTIDE NAMETK peptide
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytosol, ER and Golgi body
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYHigh
PROPOSED UPTAKE MECHANISMElectrostatic attraction and clathrin-mediated endocytosis
INVITRO/INVIVOIn vitro and in vivo
CELL LINEC26 cells and HepG2 cells
In VIVO MODELBALB/C mice
CARGONanoparticle (Liposomes)
PMID23891517
PATENTUnknown
LENGTH20
Secondary StructureCCSCSSSCCHHHHHHHTTTC
SMILESN[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N
Tertiary Structure
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