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This page gives details of CPPsite entry with ID 2127
Primary information
CPPsite ID2127
PEPTIDE SEQUENCEKWFKIQMQIRRWKNKR
PEPTIDE NAMEPenetraMax
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYIncreasing concentrations of PenetraMax (0.5 or 2mM) enhanced the permeability of the nasal mucosa to insulin more markedly than L-penetratin and insulin alone
INVITRO/INVIVOIn vivo
In VIVO MODELMale Sprague Dawley rats
CARGOProtein (Insulin)
PMID24060698
PATENTUnknown
LENGTH16
Secondary StructureCCCCCCSHHHHHSCCC
SMILESN[C@@H](CCCC[NH3])C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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