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This page gives details of CPPsite entry with ID 2133
Primary information
CPPsite ID2133
PEPTIDE SEQUENCEHHHHHHHHRRRRRRRR
PEPTIDE NAMESTR-H8R8
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONStearylation
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYHigherthan R8 and H8R8
PROPOSED UPTAKE MECHANISMEndocytosis
INVITRO/INVIVOIn vitro
CELL LINECHO-K1 cells, HeLa
CARGONucleic acid (GAPDH siRNA)
PMID25193363
PATENTUnknown
LENGTH16
Secondary StructureCCTTCCCSSGGGGTCC
SMILESN[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CC=C)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNCN)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O.NC.N.N
Tertiary Structure
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  (PEPstrMOD)