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This page gives details of CPPsite entry with ID 2140
Primary information
CPPsite ID2140
PEPTIDE SEQUENCEHHHHHHHHHHHHHHHHHHHHRRRRRRRRRRRRRRR
PEPTIDE NAMESTR-H20R8
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONStearylation
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYHigher than all the sterylated forms
PROPOSED UPTAKE MECHANISMEndocytosis
INVITRO/INVIVOIn vitro
CELL LINECHO-K1 cells, HeLa
CARGONucleic acid (GAPDH siRNA)
PMID25193363
PATENTUnknown
LENGTH35
Secondary StructureCTTTTSSSCCSSSCTTTTTHHHHHHHHHHHHHHHC
SMILESN[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C=O)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCN
Tertiary Structure
(Technique)
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 (Homology based)