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This page gives details of CPPsite entry with ID 2232
Primary information
CPPsite ID2232
PEPTIDE SEQUENCEYARVRRRGPRR
PEPTIDE NAMEHph-1
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
N-TERMINAL MODIFICATIONConjugation with 6-histidine tag
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHighly efficient at delivering siRNA in vitro
INVITRO/INVIVOIn vitro and in vivo
CELL LINEHeLa
In VIVO MODELMale C57BL/6J (H-2b) mice
CARGONucleic acid (Hph1Hph1dsRBD/FAM-labeled siRNA complex)
PMID24768403
PATENTUnknown
LENGTH11
Secondary StructureCCSSCCCCTTC
SMILESN[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)