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This page gives details of CPPsite entry with ID 2235
Primary information
CPPsite ID2235
PEPTIDE SEQUENCECRRLRHLRHHYRRRWHRFRC
PEPTIDE NAMEMgpe-9
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYSecondary Amphipathic
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
CHEMICAL MODIFICATIONAddition of cysteine in Mgpe3 sequence makes Mgpe9
UPTAKE EFFICIENCYMost efficient peptide for DNA uptake (comparison to Mgpe-3)
INVITRO/INVIVOIn vitro
CELL LINEA549, MCF-7, HeLa, HEK, T47D, B16, MDA-MB 231, B35 and U 87, CHO-K1, H-1299, JURKAT and RAW
CARGONucleic acid (Plasmid DNA)
PMID24816284
PATENTUnknown
LENGTH20
Secondary StructureCCSCCHHHHHHHTTCCCCCC
SMILESN[C@@H](CS)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC1=CNCN1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CS)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)