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This page gives details of CPPsite entry with ID 2267
Primary information
CPPsite ID2267
PEPTIDE SEQUENCEPKKKRKV-RRRRRRR-PQMQQNVFQYPGAGMVPQGEANF
PEPTIDE NAMER7-SRC1(1222-1245)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONConjugated with NLS
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYLower uptake efficiency than TP10-SRC1LXXLL
INVITRO/INVIVOIn vitro
CELL LINEMCF-7, MDA-MB-231, and HeLa
CARGOFluorophore (FITC )
PMID24705462
PATENTUnknown
LENGTH37
Secondary StructureCHHHHHHHHHHHHTHHHHHHHHHTTSSCSCCTTTTTC
SMILESN1[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C=O)Cc3ccccc3)CC(=O)N)C)CCC(=O)O)CCC(=O)N)CCC)C(C)C)CCSC)C)CCC2)Cc2ccc(cc2
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (Homology based)