This page gives details of CPPsite entry with ID 2290 |
Primary information | |
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CPPsite ID | 2290 |
PEPTIDE SEQUENCE | EEEEEEEEPLGLAGRRRRRRRRN |
PEPTIDE NAME | ACPP |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
SUB CELLULAR LOCALIZATION | Cytoplasm |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | Higher uptake efficiency |
PROPOSED UPTAKE MECHANISM | Endocytotic process |
INVITRO/INVIVO | In vitro and in vivo |
CELL LINE | A549, MDA-MB-231, Human bronchial epithelial (HBE) cells and HepG2 and Recombinant Ad5 viruses |
In VIVO MODEL | Male and female bufo gargarizans and male and female Sprague-Dawley(SD) rats |
CARGO | ACPP-HPMA Copolymer-Coated Adenovirus Conjugates |
PMID | 25000246 |
PATENT | Unknown |
LENGTH | 23 |
Secondary Structure | CCSBSSSSCBSSSCSGGGGGSCC |
SMILES | N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(=O)N |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |