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This page gives details of CPPsite entry with ID 2290
Primary information
CPPsite ID2290
PEPTIDE SEQUENCEEEEEEEEEPLGLAGRRRRRRRRN
PEPTIDE NAMEACPP
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigher uptake efficiency
PROPOSED UPTAKE MECHANISMEndocytotic process
INVITRO/INVIVOIn vitro and in vivo
CELL LINEA549, MDA-MB-231, Human bronchial epithelial (HBE) cells and HepG2 and Recombinant Ad5 viruses
In VIVO MODELMale and female bufo gargarizans and male and female Sprague-Dawley(SD) rats
CARGOACPP-HPMA Copolymer-Coated Adenovirus Conjugates
PMID25000246
PATENTUnknown
LENGTH23
Secondary StructureCCSBSSSSCBSSSCSGGGGGSCC
SMILESN[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(=O)N
Tertiary Structure
(Technique)
View in Jmol  OR Download Structure
 (PEPstrMOD)