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This page gives details of CPPsite entry with ID 2294
Primary information
CPPsite ID2294
PEPTIDE SEQUENCERQIKIWFQNRRMKWKK
PEPTIDE NAMEF(SG)4Pen
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic and amphipathic
N-TERMINAL MODIFICATIONAcetylation
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYHigher uptake efficiency for BSA
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHeLa, KG1a cells
CARGOFluorophore (Alexa488), Protein (bovine serum albumin) and Nanoparticle (quantum dots)
PMID25108152
PATENTUnknown
LENGTH16
Secondary StructureCCCSSHHHHHHSSSCC
SMILES[NH3][C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCC[NH3])CCCC[NH3])Cc1c[nH]c2c1cccc2)CCCC[NH3])CCSC)CCCNC(=[NH2])N)CCCNC(=[NH2])N)CC(=O)N)CCC(=O)N)Cc1ccccc1)Cc1c[nH]c2c1cccc2)[C@H](CC)C)CCCC[NH3])[C@H](CC)C)CCC(=O)N)CCCNC(=[NH2])N
Tertiary Structure
(Technique)
View in Jmol  OR Download Structure
 (Experimentally determined structure from PDB)