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This page gives details of CPPsite entry with ID 2313
Primary information
CPPsite ID2313
PEPTIDE SEQUENCEKETWWETWWTEWSQPKKKRKV
PEPTIDE NAMEPEP-1
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYLower uptake efficiency
INVITRO/INVIVOIn vitro and in vivo
CELL LINECT26 mouse colon cancer cells, HeLa and Hep3B cells
In VIVO MODELMale Balb/c mice
CARGOPeptide (Mitochondrial Target Domain of NOXA)
PMID24416126
PATENTUnknown
LENGTH21
Secondary StructureCCSTTHHHHTTTSCSSGGGTC
SMILESN[C@@H](CCCC[NH3])C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C(
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)