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This page gives details of CPPsite entry with ID 2317
Primary information
CPPsite ID2317
PEPTIDE SEQUENCEYGRKKRRQRRR
PEPTIDE NAMETAT(47-57)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONBiotinylation
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYLower than penetratin and R6W4
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINECHO-K1 (WT) and xylose transferase- or GAG-deficient CHO-pgsA745 cells (GAGneg)
CARGOBiotin-gly4
PMID25112713
PATENTUnknown
LENGTH11
Secondary StructureCGGGGGGGGCC
SMILESN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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  (PEPstrMOD)