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This page gives details of CPPsite entry with ID 2337
Primary information
CPPsite ID2337
PEPTIDE SEQUENCEKKLFKKILKKL
PEPTIDE NAMECF-BP16
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYHigh (compare to Tat)
PROPOSED UPTAKE MECHANISMClathrin dependent endocytosis
INVITRO/INVIVOIn vitro
CELL LINEMCF-7, CAPAN-1 and mouse embryonic fibroblast 3T3
CARGOFluorophore [5(6)-carboxyfluorescein (CF)]
PMID24480922
PATENTUnknown
LENGTH11
Secondary StructureCHHHHTTTTTC
SMILESN[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)