This page gives details of CPPsite entry with ID 2352 |
Primary information | |
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CPPsite ID | 2352 |
PEPTIDE SEQUENCE | ACSGRGRGCGRGRGSCG |
PEPTIDE NAME | IA4b |
CHIRALITY | L |
LINEAR/CYCLIC | Cyclic |
SOURCE | Synthetic |
CATEGORY | Arginine rich |
SUB CELLULAR LOCALIZATION | Vesicles |
N-TERMINAL MODIFICATION | Extended with Alanine and an 6-aminohexanoic acid (Ahx) spacer |
C-TERMINAL MODIFICATION | Amidation |
UPTAKE EFFICIENCY | Lower uptake efficiency |
PROPOSED UPTAKE MECHANISM | Endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | HeLa |
CARGO | Fluorophore (FITC) |
PMID | 24697151 |
PATENT | Unknown |
LENGTH | 17 |
Secondary Structure | CTTCCSSSSSSCCSSCC |
SMILES | N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)NCC=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |