Welcome to Entry Card of Peptide


This page gives details of CPPsite entry with ID 2359
Primary information
CPPsite ID2359
PEPTIDE SEQUENCEACSDRFRNCPADEALCG
PEPTIDE NAMEkCA2 (Kallikrein inhibitor with internal arginines)
CHIRALITYL
LINEAR/CYCLICCyclic
SOURCESynthetic
CATEGORYArginine rich
SUB CELLULAR LOCALIZATIONVesicles
N-TERMINAL MODIFICATIONExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer
C-TERMINAL MODIFICATIONAmidation
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHeLa
CARGOFluorophore (FITC)
PMID24697151
PATENTUnknown
LENGTH17
Secondary StructureCCSSTTCSSSCSTTSCC
SMILESN[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)NCC=O
Tertiary Structure
(Technique)
View in Jmol  OR Download Structure
 (PEPstrMOD)