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This page gives details of CPPsite entry with ID 2447
Primary information
CPPsite ID2447
PEPTIDE SEQUENCERRIRPRPPRLPRPRPRPLPFPRPG
PEPTIDE NAMEp21-ELP1-Bac
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
SUB CELLULAR LOCALIZATIONNucleus
N-TERMINAL MODIFICATIONConjugated with p21-ELP1
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigher uptake efficiency
INVITRO/INVIVOIn vitro and in vivo
CELL LINES2013, Mia PaCa-2 and Panc-1
In VIVO MODELFemale athymic nude mice (Ncr-nu/nu)
CARGOPeptide (p21-ELP)
PMID24680816
PATENTUnknown
LENGTH24
Secondary StructureCCCCCCCSCCSSCSSCCSSCCCCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)