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This page gives details of CPPsite entry with ID 2452
Primary information
CPPsite ID2452
PEPTIDE SEQUENCEGGVCPKILKKCRRDSDCPGACICRGNGYCGSGSD
PEPTIDE NAMEMCoTI-II
CHIRALITYL
LINEAR/CYCLICCyclic
SOURCESynthetic
CATEGORYCationic
N-TERMINAL MODIFICATIONConjugation with Alexa Flour 488
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigher uptake efficiency
PROPOSED UPTAKE MECHANISMMacropinocytosis, endocytosis
INVITRO/INVIVOIn vitro
CELL LINEHeLa
CARGOFluorophore (Alexa Fluor 488)
PMID24985034
PATENTUnknown
LENGTH34
Secondary StructureCCBCCSCCCBCSSGGGSCSSCEEETTTEEECSBC
SMILESNCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H]1C(=O)N2[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]4C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]5C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C=O)CC(=O)O)CO)CO)CS[S@@](SC3)(C4)SC5)Cc3ccc(cc3)O)CC(=O)N)CCCNC(=N)N)[C@H](CC)C)CSSC1)C)CCC)CC(=O)O)CO)CC(=O)O)CCCNC(=N)N)CCCN
Tertiary Structure
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  (Homology based)