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This page gives details of CPPsite entry with ID 2470
Primary information
CPPsite ID2470
PEPTIDE SEQUENCEVSRRRRRRGGRRRR
PEPTIDE NAMEC24-LMWP
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONNucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigher uptake efficiency
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro and in vivo
CELL LINEA549/T and MCF-7/ADR
In VIVO MODELBALB/c-nu nude mice
CARGONanoparticle (LMWP/PLGA nanoparticles), Small molecule drug (Doxorubicin)
PMID25003794
PATENTUnknown
LENGTH14
Secondary StructureCCGGGSSCCCCCCC
SMILESN[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)