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This page gives details of CPPsite entry with ID 2534
Primary information
CPPsite ID2534
PEPTIDE SEQUENCERRRRRRRRR
PEPTIDE NAMERVG-9LR
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONConjugated with RVG
C-TERMINAL MODIFICATIONConjugation with siFITC complex
UPTAKE EFFICIENCYLower uptake efficiency than D form
PROPOSED UPTAKE MECHANISMReceptor-mediated endocytosis
INVITRO/INVIVOIn vitro
CELL LINENeuro2a, Jurkat cells
CARGONucleic acid (siRNA)
PMID25544044
PATENTUnknown
LENGTH9
Secondary StructureCGGGGGCCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)