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This page gives details of CPPsite entry with ID 2652
Primary information
CPPsite ID2652
PEPTIDE SEQUENCEKLALKLALKALKAALKLA
PEPTIDE NAMECyt c-ss-MAP
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONNucleus
N-TERMINAL MODIFICATIONConjugated to Radiolabeled cytochrome c with disulphide linkage
UPTAKE EFFICIENCY38-fold higher uptake for Cyt c-ss-MAP compared to unmodified Cyt c was observed
PROPOSED UPTAKE MECHANISMEndocytosis
INVITRO/INVIVOIn vitro
CELL LINEHEK293 cells and HeLa cells
CARGOProtein (Cyt C protein)
PMID22225540
PATENTUnknown
LENGTH18
Secondary StructureCCHHHHHHHHHHHHTTCC
SMILESN[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C=O
Tertiary Structure
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  (PEPstrMOD)