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This page gives details of CPPsite entry with ID 2680
Primary information
CPPsite ID2680
PEPTIDE SEQUENCERRR
PEPTIDE NAMETMR-R3
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONConjugation with TMR
UPTAKE EFFICIENCYWith pyrenebutyrate, p53-3R was mainly observed in the Nucleus whereas without pyrenebutyrate, it existed in the Cytoplasm
PROPOSED UPTAKE MECHANISMlipid raft dependent macropinocytosis
INVITRO/INVIVOIn vitro
CELL LINEU251-MG, HeLa, HEK293 cells, LNZ308, K562 cells, Primary rat fibroblasts cells and U87 cells
CARGOFluorophore (TMR)
PMID22465335
PATENTUnknown
LENGTH3
Secondary StructureCCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)