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This page gives details of CPPsite entry with ID 2690
Primary information
CPPsite ID2690
PEPTIDE SEQUENCEFFLIPKGRRRRRRRRGC
PEPTIDE NAMEPasR8 (Alexa)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytosol
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYPasR8(Alexa) efficiently internalizes into cells a few minutes after peptide administration
PROPOSED UPTAKE MECHANISMMacropinocytosis
INVITRO/INVIVOIn vitro
CELL LINEHeLa, T98G glioma cells
CARGOFluorophore (Alexa)
PMID22486588
PATENTUnknown
LENGTH17
Secondary StructureCTTSSCSSGGGGGGTCC
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCC[NH3])C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)N[C@@H](CS)C(=O)N
Tertiary Structure
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  (PEPstrMOD)