This page gives details of CPPsite entry with ID 2719 |
Primary information | |
---|---|
CPPsite ID | 2719 |
PEPTIDE SEQUENCE | GLWWKAWWKAWWKSLWWRKRKRKA |
PEPTIDE NAME | CADY-1 |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
CATEGORY | Amphipathic |
UPTAKE EFFICIENCY | Compared to free doxorubicin, the CADY-1/doxorubicin complex exhibited remarkable cell death activity |
INVITRO/INVIVO | In vitro and in vivo |
CELL LINE | The HeLa cells |
In VIVO MODEL | Human tumour xenograft female DBA/2 mice |
CARGO | Small molecule drug (Doxorubicin) |
PMID | 22688249 |
PATENT | Unknown |
LENGTH | 24 |
Secondary Structure | CCCTTTTHHHHHHHHHHHHHHHCC |
SMILES | NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |