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This page gives details of CPPsite entry with ID 2728
Primary information
CPPsite ID2728
PEPTIDE SEQUENCEYGRKKRPQRRR
PEPTIDE NAME1 (TAT)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
UPTAKE EFFICIENCYlow penetration into normal fibroblasts
INVITRO/INVIVOIn vitro and in vivo
CELL LINEMany Human neoplastic cells including HeLa, Lovo, A549, MCF-7,MKN45,HepG2, LNCap, KPK,U2OS, RC-15,RD-ES,H28,K562,U251,NHDF
In VIVO MODELNOD-SCID mice model of xenograft human tumour cells
CARGOFluorophore (FITC)
PMID22805558
PATENTUnknown
LENGTH11
Secondary StructureCTTSCCSCCCC
SMILESN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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  (PEPstrMOD)