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This page gives details of CPPsite entry with ID 2821
Primary information
CPPsite ID2821
PEPTIDE SEQUENCEVSRRRRRRGGRRRR
PEPTIDE NAMElow molecular weight protamine (LMWP)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEChimeric
CATEGORYCationic
N-TERMINAL MODIFICATIONSulfhydrylation
C-TERMINAL MODIFICATIONFree
CHEMICAL MODIFICATIONSulfhydrylation
UPTAKE EFFICIENCYEquivalent cell-internalization potency to that of TAT
INVITRO/INVIVOIn vitro and in vivo
CELL LINECaco-2 cell culture
In VIVO MODELMale Wistar rats
CARGOProtein (Insulin-PEG-LMWP)
PMID23863452
PATENTUnknown
LENGTH14
Secondary StructureCHHHHHCCCCCSCC
SMILESN[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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  (PEPstrMOD)