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Details of CPPsite entry with Sequence CRGDKGPDC
Primary information
PEPTIDE SEQUENCECRGDKGPDC
CPPsite ID 2081, 2557,
PEPTIDE NAMEiRGD-CDD, PC-CC9/miRNA
CHIRALITYL, L
LINEAR/CYCLICLinear, Cyclic
SOURCESynthetic, Synthetic
CATEGORYNA, Cationic
SUB CELLULAR LOCALIZATIONCytoplasm, NA
N-TERMINAL MODIFICATIONFree, Free
C-TERMINAL MODIFICATIONFree, Free
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYNA, PC-CC9/FAM-siRNA and PC/ FAM-siRNA CC9 could approach PANC-1 cells quickly
PROPOSED UPTAKE MECHANISMNA, NA
INVITRO/INVIVOIn vitro and in vivo, In vitro and in vivo
CELL LINEHuman embryonic kidney (HEK) 293T, prostate cancer PPC1,mouse breast cancer 4T1, Human tumor cell line M21, Human breast cancer cell line MCF-10CA1a, PANC-1 and 293T cells
In VIVO MODELAthymic nude mice and Balb/C mice, Mice
CARGOFluorophore (Red fluorophor Dy550), Nucleic acid (miRNA)
PMID23248118, 23298779
PATENTUnknown, Unknown
Tertiary Structure
(Technique)		2081 (PEPstrMOD), 2557 (PEPstrMOD),