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Details of CPPsite entry with Sequence EEEEEEEEEE-PLGLAG-VSRRRRRRGGRRRR
Primary information
PEPTIDE SEQUENCEEEEEEEEEEE-PLGLAG-VSRRRRRRGGRRRR
CPPsite ID 2070,
PEPTIDE NAMEALWMP
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
CHEMICAL MODIFICATIONLinker (PLGLAG)
PROPOSED UPTAKE MECHANISMClathrin-mediated and cytoskeleton-dependent endocytosis as well as energy independent internalization
INVITRO/INVIVOIn vitro and in vivo
CELL LINEHT-1080 and brain capillary endothelial cell bEnd.3 cell line
In VIVO MODELAdult male BALB/c nude mice and male SpragueDawley rats
CARGONanoparticles and Fluoriophore (coumarin-6)
PMID23350619
PATENTUnknown
Tertiary Structure
(Technique)
2070 (I-TASSER),