Welcome to Sequence Card of Peptide


Details of CPPsite entry with Sequence IPLVVPLRRRRRRRRC
Primary information
PEPTIDE SEQUENCEIPLVVPLRRRRRRRRC
CPPsite ID 2215, 2598,
PEPTIDE NAMERIPL, RIPL peptide
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCEChimeric, Synthetic
CATEGORYCationic, NA
SUB CELLULAR LOCALIZATIONCytoplasm, NA
N-TERMINAL MODIFICATIONFree, Free
C-TERMINAL MODIFICATIONFree, Free
CHEMICAL MODIFICATIONRIPL peptides is conjugated to maleimide-derivatized liposomal vesicles via the thiol-maleimide reaction, NA
UPTAKE EFFICIENCYIncreased from 20 to 70 fold compared to FITC dextran, NA
PROPOSED UPTAKE MECHANISMEndocytic pathway, NA
INVITRO/INVIVOIn vitro, In vitro
CELL LINELNCaP, SK-OV-3, and MCF-7 as Hpn-expressing cells, DU-145, PC-3, and HaCaT as Hpn-non-expressing cells, LNCaP, SK-OV-3, MCF-7, DU-145, PC-3, and HaCaT
In VIVO MODELNA, NA
CARGOFluorophore (FITC), Nanoparticle (Liposomes), Fluorophore (FITC)
PMID24704199, 24704199
PATENTUnknown, Unknown
Tertiary Structure
(Technique)		2215 (PEPstrMOD), 2598 (PEPstrMOD),