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Details of CPPsite entry with Sequence K-Hey-FQWQRNMRKVRGPPVS-Hey-IKR
Primary information
PEPTIDE SEQUENCEK-Hey-FQWQRNMRKVRGPPVS-Hey-IKR
CPPsite ID 2192,
PEPTIDE NAMEhLF Hcy
CHIRALITYModified
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytosol and Nucleus
N-TERMINAL MODIFICATIONConjugation with 5(6)-Carboxyfluorescein
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONhcy, homocysteine in which the side chain is one methylene group longer than in cysteine
UPTAKE EFFICIENCYEqual to hLF Wt
PROPOSED UPTAKE MECHANISMEndocytosis and acid sphingomyelinase-dependent induction of nucleation zones (NZ)
INVITRO/INVIVOIn vitro
CELL LINEHeLa, Jurkat E6.1 leukemia cells, Ovcar-3 cells, and Caco-2 cells
CARGOFluorophore (Fluorescein)
PMID24270856
PATENTUnknown
Tertiary Structure
(Technique)		Not Predicted),