Welcome to Sequence Card of Peptide
Details of CPPsite entry with Sequence KFFKFFKFFK |
| Primary information | |
|---|---|
| PEPTIDE SEQUENCE | KFFKFFKFFK |
| CPPsite ID | 2072, 2073, 2074, 2075, 2076, 2077, 2078, 2079, 2080, 2510, |
| PEPTIDE NAME | CPP-PNA, CPP-PNA, CPP-PNA, CPP-PNA, CPP-PNA, CPP-PNA, CPP-PNA, CPP-PNA, CPP-PNA, (KFF)3K |
| CHIRALITY | L, L, L, L, L, L, L, L, L, L |
| LINEAR/CYCLIC | Linear, Linear, Linear, Linear, Linear, Linear, Linear, Linear, Linear, Linear |
| SOURCE | Synthetic, Synthetic, Synthetic, Synthetic, Synthetic, Synthetic, Synthetic, Synthetic, Synthetic, Synthetic |
| CATEGORY | NA, NA, NA, NA, NA, NA, NA, NA, NA, Cationic |
| SUB CELLULAR LOCALIZATION | NA, NA, NA, NA, NA, NA, NA, NA, NA, Cytoplasm |
| N-TERMINAL MODIFICATION | Free, Free, Free, Free, Free, Free, Free, Free, Free, Free |
| C-TERMINAL MODIFICATION | Conjugation with nucleic acid, Conjugation with nucleic acid, Conjugation with nucleic acid, Conjugation with nucleic acid, Conjugation with nucleic acid, Conjugation with nucleic acid, Conjugation with nucleic acid, Conjugation with nucleic acid, Conjugation with nucleic acid, Conjugated LNA with a Cys-succinimidyl trans-4-(maleimidylmethyl)cyclo- hexane-1-carboxylate-C6 (Cys-SMCC-C6) linker |
| CHEMICAL MODIFICATION | Nucleic acid is attached via an ethylene glyol linker, Nucleic acid is attached via an ethylene glyol linker, Nucleic acid is attached via an ethylene glyol linker, Nucleic acid is attached via an ethylene glyol linker, Nucleic acid is attached via an ethylene glyol linker, Nucleic acid is attached via an ethylene glyol linker, Nucleic acid is attached via an ethylene glyol linker, Nucleic acid is attached via an ethylene glyol linker, Nucleic acid is attached via an ethylene glyol linker, NA |
| UPTAKE EFFICIENCY | NA, NA, NA, NA, NA, NA, NA, NA, NA, Higher uptake efficiceny |
| PROPOSED UPTAKE MECHANISM | NA, NA, NA, NA, NA, NA, NA, NA, NA, NA |
| INVITRO/INVIVO | In vitro and in vivo, In vitro and in vivo, In vitro and in vivo, In vitro and in vivo, In vitro and in vivo, In vitro and in vivo, In vitro and in vivo, In vitro and in vivo, In vitro and in vivo, In vitro and in vivo |
| CELL LINE | J774A.1, J774A.1, J774A.1, J774A.1, J774A.1, J774A.1, J774A.1, J774A.1, J774A.1, Gastric mucosal epithelial cells |
| In VIVO MODEL | Brucella suis 1330, B. melitensis 16M and Brucella abortus 2308, Brucella suis 1330, B. melitensis 16M and Brucella abortus 2308, Brucella suis 1330, B. melitensis 16M and Brucella abortus 2308, Brucella suis 1330, B. melitensis 16M and Brucella abortus 2308, Brucella suis 1330, B. melitensis 16M and Brucella abortus 2308, Brucella suis 1330, B. melitensis 16M and Brucella abortus 2308, Brucella suis 1330, B. melitensis 16M and Brucella abortus 2308, Brucella suis 1330, B. melitensis 16M and Brucella abortus 2308, Brucella suis 1330, B. melitensis 16M and Brucella abortus 2308, C57BL/6J mice |
| CARGO | PNA, PNA, PNA, PNA, PNA, PNA, PNA, PNA, PNA, Nucliec acid (LNA) |
| PMID | 23305655, 23305655, 23305655, 23305655, 23305655, 23305655, 23305655, 23305655, 23305655, 25421468 |
| PATENT | Unknown, Unknown, Unknown, Unknown, Unknown, Unknown, Unknown, Unknown, Unknown, Unknown |
| Tertiary Structure (Technique) | 2072 (PEPstrMOD), 2073 (PEPstrMOD), 2074 (PEPstrMOD), 2075 (PEPstrMOD), 2076 (PEPstrMOD), 2077 (PEPstrMOD), 2078 (PEPstrMOD), 2079 (PEPstrMOD), 2080 (PEPstrMOD), Not Predicted), |