Welcome to Sequence Card of Peptide
Details of CPPsite entry with Sequence KKWKMRRNQFWIKIQR |
| Primary information | |
|---|---|
| PEPTIDE SEQUENCE | KKWKMRRNQFWIKIQR |
| CPPsite ID | 2545, 2546, 1091, |
| PEPTIDE NAME | CF-Penetratin-substrate, Ac-Penetratin-substrate, pAntpHD (58-43) |
| CHIRALITY | L, L, L |
| LINEAR/CYCLIC | Linear, Linear, Linear |
| SOURCE | Protein derived, Protein derived, Protein derived |
| CATEGORY | Cationic and amphipathic, Cationic and amphipathic, Amphipathic |
| SUB CELLULAR LOCALIZATION | Cytosol, Cytosol, Cytoplasm and nucleus |
| N-TERMINAL MODIFICATION | Conjugation with 5(6)-Carboxyfluorescein, Acetylation, Biotinylation |
| C-TERMINAL MODIFICATION | Conjugation with substrate, Conjugation with substrate, Amidation |
| CHEMICAL MODIFICATION | NA, NA, NA |
| UPTAKE EFFICIENCY | NA, NA, Similar to (pAntp) (43-58) |
| PROPOSED UPTAKE MECHANISM | Endosomal uptake, Endosomal uptake, Non-receptor mdiated endocytic pathway |
| INVITRO/INVIVO | In vitro, In vitro, In vitro |
| CELL LINE | HeLa Cells, HeLa Cells, Cortical striatal cells |
| In VIVO MODEL | NA, NA, NA |
| CARGO | Fluorophore (Fluorescein), substrate, Fluorophore (Fluorescein), substrate, Biotin |
| PMID | 23621550, 23621550, 8663410 |
| PATENT | Unknown, Unknown, Unknown |
| Tertiary Structure (Technique) | 2545 (PEPstrMOD), 2546 (PEPstrMOD), 1091 (PEPstrMOD), |