Welcome to Sequence Card of Peptide
Details of CPPsite entry with Sequence LLIILRRRIRKQAHAHSK |
| Primary information | |
|---|---|
| PEPTIDE SEQUENCE | LLIILRRRIRKQAHAHSK |
| CPPsite ID | 2039, 2224, 2428, 2566, 2613, 1296, |
| PEPTIDE NAME | FAM-pVEC, EGFP-pVEC, pVEC, pVEC-EGFP, pVEC, pVEC |
| CHIRALITY | L, L, L, L, L, L |
| LINEAR/CYCLIC | Linear, Linear, Linear, Linear, Linear, Linear |
| SOURCE | Protein derived, Protein derived, Protein derived, Protein derived, Protein derived, Protein derived |
| CATEGORY | NA, Amphipathic, Amphipathic, Amphipathic, Amphipathic, Amphipathic |
| SUB CELLULAR LOCALIZATION | NA, NA, Cytoplasm, NA, Cytoplasm, Cytoplasm and nucleus |
| N-TERMINAL MODIFICATION | Conjugation with 5(6)-Carboxyfluorescein, Conjugated with EGFP, Free, Conjugation with EGFP, NA, Conjugation with fluorescein |
| C-TERMINAL MODIFICATION | Amidation, Free, Amidation, Free, NA, Amidation |
| CHEMICAL MODIFICATION | NA, NA, NA, NA, NA, NA |
| UPTAKE EFFICIENCY | NA, NA, NA, NA, High, High |
| PROPOSED UPTAKE MECHANISM | NA, NA, Clathrin dependent uptake, NA, Direct cellular penetration, Receptor independent endocytic pathway |
| INVITRO/INVIVO | In vitro and in vivo, In vitro, In vitro, In vitro and in vivo, In vitro, In vitro |
| CELL LINE | HEK 293, human glioma, U87 MG and HeLa, Mouse macrophage-like cell line J774 A.4, HeLa, CHO and Jurkat cells, The mouse macrophage J774 A.1 cells, CHO-K1 and WM266-1 cells, AEC, HBCEC, End and Human bowes melanoma cells |
| In VIVO MODEL | Female nude mice, NA, NA, Zebrafish, NA, NA |
| CARGO | Fluorophore [5(6)-carboxyfluorescein (FAM)], Protein (eGFP), Fluorophore [5(6)-carboxyfluorescein], Protein (eGFP), Nucleic acid (Plasmid DNA), Fluorophore (fluorescein) |
| PMID | 23350661, 24746937, 24870379, 24746937, 21996011, 16808894 |
| PATENT | Unknown, Unknown, Unknown, Unknown, Unknown, Unknown |
| Tertiary Structure (Technique) | 2039 (PEPstrMOD), 2224 (PEPstrMOD), 2428 (PEPstrMOD), 2566 (PEPstrMOD), 2613 (PEPstrMOD), 1296 (PEPstrMOD), |