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Details of CPPsite entry with Sequence MVTVLFRRLRIRRACGPPRVRV
Primary information
PEPTIDE SEQUENCEMVTVLFRRLRIRRACGPPRVRV
CPPsite ID 2157, 3000, 3009, 1447,
PEPTIDE NAMEM918, Pepfect 2, M918, M918
CHIRALITYL, Modified, L, L
LINEAR/CYCLICLinear, Linear, Linear, Linear
SOURCESynthetic, Synthetic, Synthetic, Protein derived
CATEGORYNA, NA, NA, Amphipathic
SUB CELLULAR LOCALIZATIONNA, NA, NA, Vesicles
N-TERMINAL MODIFICATIONFree, Stearylation, NA, Conjugation with fluorescein
C-TERMINAL MODIFICATIONFree, Amidation, Amidation, Amidation
CHEMICAL MODIFICATIONNA, NA, NA, NA
UPTAKE EFFICIENCYNA, NA, NA, Higher than Penetratin
PROPOSED UPTAKE MECHANISMEndocytosis, Endocytosis, Endocytosis, Mainly via endocytic process,and in particular macropinocytosis, but independent of glycosaminoglycans on the cell surface
INVITRO/INVIVOIn vitro, In vitro, In vitro, In vitro
CELL LINEHT-29-luc cells, HeLa cells, HeLa cells, HeLa, MCF-7, CHO K1, and Hifko cells
In VIVO MODELNA, NA, NA, NA
CARGOPNA, Nucelic acid (pGL3 plasmid, SCO), Nucleic acid (SCO), Fluorophore (fluorescein)
PMID25185512, 17622242
PATENTUnknown, US 2014/0140929 A1, US 2014/0140929 A1, Unknown
Tertiary Structure
(Technique)		2157 (PEPstrMOD), 3000 (PEPstrMOD), 3009 (PEPstrMOD), 1447 (PEPstrMOD),