Details of CPPsite entry with Sequence Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg |
| Primary information | |
|---|---|
| PEPTIDE SEQUENCE | Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg |
| CPPsite ID | 2747, |
| PEPTIDE NAME | Polyguanidine comparators 2 |
| CHIRALITY | Modified |
| LINEAR/CYCLIC | Linear |
| SOURCE | Synthetic |
| CATEGORY | Cationic and amphipathic |
| SUB CELLULAR LOCALIZATION | Cytoplasm |
| N-TERMINAL MODIFICATION | Conjugation with 5(6)-Carboxyfluorescein |
| C-TERMINAL MODIFICATION | Amidation |
| CHEMICAL MODIFICATION | Peptoids (poly-N-substituted glycines) |
| UPTAKE EFFICIENCY | Medium (comapre to Polyguanidine comparator 1) |
| PROPOSED UPTAKE MECHANISM | Energy-independent internalization |
| INVITRO/INVIVO | In vitro |
| CELL LINE | MCF-7 cells |
| CARGO | Fluorophore [5(6)-Carboxyfluorescein (CF)] |
| PMID | 22828784 |
| PATENT | Unknown |
| Tertiary Structure (Technique) | Not Predicted), |