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Details of CPPsite entry with Sequence PKKKRKV-AGYLLGKINLKALAALAKKIL-PQMQQNVFQYPGAGMVPQGEANF
Primary information
PEPTIDE SEQUENCEPKKKRKV-AGYLLGKINLKALAALAKKIL-PQMQQNVFQYPGAGMVPQGEANF
CPPsite ID 2264, 2266,
PEPTIDE NAMETP10-SRC1LXXLL, TP10-SRC1(1222-1245)
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCEChimeric, Chimeric
CATEGORYCationic, Cationic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus, Cytoplasm and Nucleus
N-TERMINAL MODIFICATIONConjugated with NLS, Conjugated with NLS
C-TERMINAL MODIFICATIONFree, Free
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYHigher uptake efficiency, Lower uptake efficiency than TP10-SRC1LXXLL
PROPOSED UPTAKE MECHANISMNA, NA
INVITRO/INVIVOIn vitro, In vitro
CELL LINEMCF-7 cells, MCF-7 cells
In VIVO MODELNA, NA
CARGOFluorophore (FITC ), Fluorophore (FITC )
PMID24705462, 24705462
PATENTUnknown, Unknown
Tertiary Structure
(Technique)
2264 (PEPstrMOD), 2266 (I-TASSER),