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Details of CPPsite entry with Sequence RRLLRRLRR
Primary information
PEPTIDE SEQUENCERRLLRRLRR
CPPsite ID 2318, 2784,
PEPTIDE NAMER6L3, RL-9
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCESynthetic, Synthetic
CATEGORYCationic, Cationic
SUB CELLULAR LOCALIZATIONCytoplasm, NA
N-TERMINAL MODIFICATIONBiotinylation, NA
C-TERMINAL MODIFICATIONAmidation, Amidation
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYLower than penetratin and R6W5, NA
PROPOSED UPTAKE MECHANISMEndocytic pathway, NA
INVITRO/INVIVOIn vitro, In vitro
CELL LINECHO-K1 (WT) and xylose transferase- or GAG-deficient CHO-pgsA745 cells (GAGneg), CHO-K1
In VIVO MODELNA, NA
CARGOBiotin-gly4, Fluorophore (Alexa 488)
PMID25112713, 23524021
PATENTUnknown, Unknown
Tertiary Structure
(Technique)		2318 (PEPstrMOD), 2784 (PEPstrMOD),