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Details of CPPsite entry with Sequence RRRQRRKKRGYCKCKYGRKKRRQRRR
Primary information
PEPTIDE SEQUENCERRRQRRKKRGYCKCKYGRKKRRQRRR
CPPsite ID 2581, 2583,
PEPTIDE NAMEdfTAT, nrdfTAT
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCEProtein derived, Protein derived
CATEGORYCationic, Cationic
SUB CELLULAR LOCALIZATIONCytosol and Nucleus, Cytosol and Nucleus
N-TERMINAL MODIFICATIONExtra Cys and Lys added for labeling of TMR and dimerization, bis(maleimido)ethane added
C-TERMINAL MODIFICATIONFree, Free
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYNA, NA
PROPOSED UPTAKE MECHANISMMacropinocytosis, Macropinocytosis
INVITRO/INVIVOIn vitro, In vitro
CELL LINEHeLa, Neuro-2a and HDF cells, HeLa, Neuro-2a and HDF cells
In VIVO MODELNA, NA
CARGOProtein (eGFP), Fluorophore (TMR), Fluorophore (TMR)
PMID24930129, 24930129
PATENTUnknown, Unknown
Tertiary Structure
(Technique)
2581 (PEPstrMOD), 2583 (PEPstrMOD),