Details of CPPsite entry with Sequence TRQARRNRRRRWRERQR |
Primary information | |
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PEPTIDE SEQUENCE | TRQARRNRRRRWRERQR |
CPPsite ID | 1029, |
PEPTIDE NAME | Rev (34-50) |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Cytoplasm and nucleus |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Conjugation with fluorescein by C-terminal Cys amide |
UPTAKE EFFICIENCY | High (comparable to Tat (48-60) |
PROPOSED UPTAKE MECHANISM | Non-endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | RAW 264.7 |
CARGO | Fluorophore (fluorescein) |
PMID | 11084031 |
PATENT | US 20060223752 |
Tertiary Structure (Technique) | 1029 (Experimentally determined structure from PDB), |