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Details of CPPsite entry with Sequence TRQARRNRRRRWRERQR
Primary information
PEPTIDE SEQUENCETRQARRNRRRRWRERQR
CPPsite ID 1029,
PEPTIDE NAMERev (34-50)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with fluorescein by C-terminal Cys amide
UPTAKE EFFICIENCYHigh (comparable to Tat (48-60)
PROPOSED UPTAKE MECHANISMNon-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINERAW 264.7
CARGOFluorophore (fluorescein)
PMID11084031
PATENTUS 20060223752
Tertiary Structure
(Technique)
1029 (Experimentally determined structure from PDB),