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Details of CPPsite entry with Sequence rrrrrr
Primary information
PEPTIDE SEQUENCErrrrrr
CPPsite ID 1040,
PEPTIDE NAMED-R6
CHIRALITYD
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONProbably cytoplasm and nucleus
N-TERMINAL MODIFICATIONConjugation with fluorescein with 6-aminohexanoic acid (Ahx) spacer
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigh (comparable to Tat (49-57) and higher than R6
PROPOSED UPTAKE MECHANISMProbably non-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEJurkat
CARGOFluorophore (fluorescein)
PMID11087855
PATENTUS 6593292
Tertiary Structure
(Technique)
1040 (PEPstrMOD),