Figure:  Inhibitory mechanisms of siRNA against HIV


HIVsir is manually curated and compiled database of siRNAs reported against HIV in literature as on 18th Feb 2011. Articles were carefully examined and detailed information of more than 750 siRNAs/shRNAs including more than 100 siRNAs/shRNAs differing by one or more bases with the target sites were collected in the database. HIVsir database structure contains sixteen fields including siRNA/shRNA sequence, HIV strain, targeted genome region and efficacy. Database has standard search option using different fields, advance search options for making query by combining more fields and also browsing facility. It also have important useful tools 1) siRNA Map. 2) HIVsirDB blast.3) siRNAalign

Citation: If you are using this database, please cite:- Tyagi A, Ahmed F, Thakur N, Sharma A, Raghava GPS, et al. (2011) HIVsirDB: A Database of HIV Inhibiting siRNAs. PLoS ONE 6(10): e25917. doi:10.1371/journal.pone.0025917

Bioinformatics Center, Institute of Microbial Technology, Chandigarh-160036, India