Browse Epitopes

This module is created to browse the epitopes predicted from vaccine candidates of all mycobacterial strains. This epitopes were predicted by creating 9mer overlapping peptides from the vaccine candidates from each mycobacterial species. We used a prediction pipeline for predicting the epitopes. Currently, you are browsing B cell epitopes from our compiled results. Here, the first column represent the unique Mtbeveb ID for each peptide sequences. The ID and peptide sequence is hyperlinked to epitope card. The next column contains Gene ID, which is hyperlinked to antigen card. The next column displays the detail of protien from NCBI notation. The fourth column presents the position of the peptide in that protein. This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header. The last five columns present the fields related to MHC class II prediction using Propred followed by prediction of interferon-gamma inducing peptides. The sixth column tells us the MHC class II alleles to which peptide is binding. The seventh column counts the number of MHC class II alleles for that peptide. The eighth column depicts the prediction result of IFNepitope server with ninth column present the alogirithm of IFNepitope program. The last column display the score of peptides from IFNepitope server.


Total number of predicted 9mer peptides are 108182 (corresponding to browse type th1)



ID gene IDProtein DetailPositionSequence (9mer)MHC class II Alleles MHC class II alleles (count) IFN-gamma inducing algorithmIFN-gamma inducing Score
VIR098423449062449 YP 007429532.1 transmembranetransportproteinMmpL4[MycobacteriumbovisBCGstr.Korea1168P]369LKVRGWRRV DRB1_0402 1 MERCI 0.99
VIR098425449062449 YP 007429532.1 transmembranetransportproteinMmpL4[MycobacteriumbovisBCGstr.Korea1168P]371VRGWRRVGT DRB1_1102, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328, DRB1_1501, DRB1_1506 13 MERCI 0.99
VIR098434449062449 YP 007429532.1 transmembranetransportproteinMmpL4[MycobacteriumbovisBCGstr.Korea1168P]380VVVRWPLPV DRB1_0102, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0311, DRB1_0402, DRB1_0701, DRB1_0703, DRB1_0801, DRB1_0802, DRB1_0804, DRB1_0806, DRB1_0813, DRB1_0817, DRB1_1101, DRB1_1102, DRB1_1104, DRB1_1106, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1128, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1305, DRB1_1311, DRB1_1321, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328, DRB1_1501, DRB1_1502, DRB1_1506 35 SVM 0.23
VIR098442449062449 YP 007429532.1 transmembranetransportproteinMmpL4[MycobacteriumbovisBCGstr.Korea1168P]388VLVATCAIA DRB1_0101, DRB1_0102 2 SVM 0.38
VIR098443449062449 YP 007429532.1 transmembranetransportproteinMmpL4[MycobacteriumbovisBCGstr.Korea1168P]389LVATCAIAL DRB1_0101, DRB1_0102, DRB1_0701, DRB1_0703, DRB1_1501, DRB1_1506, DRB5_0101, DRB5_0105 8 SVM 0.48
VIR098451449062449 YP 007429532.1 transmembranetransportproteinMmpL4[MycobacteriumbovisBCGstr.Korea1168P]397LVGLLALPG DRB1_0101, DRB1_0102, DRB1_0401, DRB1_0404, DRB1_0405, DRB1_0408, DRB1_0410, DRB1_0421, DRB1_0423, DRB1_0426, DRB1_0801, DRB1_0804, DRB1_0806, DRB1_0817, DRB1_1101, DRB1_1102, DRB1_1104, DRB1_1106, DRB1_1120, DRB1_1121, DRB1_1128, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1305, DRB1_1307, DRB1_1311, DRB1_1321, DRB1_1322, DRB1_1327, DRB1_1328, DRB1_1501, DRB1_1506, DRB5_0101, DRB5_0105 35 SVM 0.23
VIR098480449062449 YP 007429532.1 transmembranetransportproteinMmpL4[MycobacteriumbovisBCGstr.Korea1168P]426YAAADRHFS DRB1_1101, DRB1_1114, DRB1_1120, DRB1_1302, DRB1_1307, DRB1_1323 6 SVM 0.36
VIR098505449062449 YP 007429532.1 transmembranetransportproteinMmpL4[MycobacteriumbovisBCGstr.Korea1168P]451MRNPADFLV DRB1_1501, DRB1_1506 2 SVM 0.16
VIR098521449062449 YP 007429532.1 transmembranetransportproteinMmpL4[MycobacteriumbovisBCGstr.Korea1168P]467IFRVPGISR DRB1_0102, DRB5_0101, DRB5_0105 3 SVM 0.12
VIR098522449062449 YP 007429532.1 transmembranetransportproteinMmpL4[MycobacteriumbovisBCGstr.Korea1168P]468FRVPGISRV DRB1_0305, DRB1_0309, DRB1_0813 3 SVM 0.96
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