Details of SAPdb entry with Sequence βAH |
| Primary information | |
|---|---|
| SAPdb ID | 1265, |
| PMID | 19904373 |
| Peptide Name | N-(4-ntetradecyloxybenzoyl)- L-carnosine |
| Peptide sequence | βAH |
| N-Terminal Modification | Acylation (4-n-tetradecyloxybenzoyl) |
| C-Terminal Modification | Free |
| Non-Terminal Modification | βA=beta-alanine |
| Length | 2 |
| Peptide/Conjuagate | Peptide |
| Technique | FE - SEM (Field Emission Scanning Electron Microscopy) |
| Solvent | 20nM Phosphate buffer |
| Method | Aqeous dispersion of peptide dissolved in phosphate buffer saline (pH7) at concentration 20nM by heating at ~70°C in water and subsequently kept at room temperature to form gel. |
| Conc | 20nM |
| Temperature | 8 |
| Temperature | 25°C |
| Year | 2009 |
| Self assembly | Yes |
| Type of Self assembly | Hydrogel (consists of interwined ribbons) |
| Tertiary Structure (Technique) | Not Predicted), |
| Linear | |
| NA | |
| Stable at Room temperature | |
| Hydrogel | |
| NA | |
| AH | |
| N.A. | |
| Primary information | |
| SAPdb ID | 1266, |
| PMID | 19904373 |
| Peptide Name | N-(4-ntetradecyloxybenzoyl)- L-carnosine |
| Peptide sequence | βAH |
| N-Terminal Modification | Acylation |
| C-Terminal Modification | Free |
| Non-Terminal Modification | βA=beta-alanine |
| Length | 2 |
| Peptide/Conjuagate | Peptide |
| Technique | FE - SEM (Field Emission Scanning Electron Microscopy) |
| Solvent | 20nM Phosphate buffer |
| Method | Aqeous dispersion of peptide dissolved in phosphate buffer saline (pH7) at concentration 20nM by heating at ~70°C in water and subsequently kept at room temperature to form self assembled structure. |
| Conc | 20nM |
| Temperature | 2 |
| Temperature | 25°C |
| Year | 2009 |
| Self assembly | Yes |
| Type of Self assembly | Bilayer Nanostructures |
| Tertiary Structure (Technique) | Not Predicted), |
| Linear | |
| NA | |
| NA | |
| Nanoparticle | |
| 3.7 | |
| AH | |
| N.A. | |
| Primary information | |
| SAPdb ID | 1487, |
| PMID | 22788380 |
| Peptide Name | L-Carnosine |
| Peptide sequence | βAH |
| N-Terminal Modification | Palmitic acid |
| C-Terminal Modification | Free |
| Non-Terminal Modification | βA=beta-alanine |
| Length | 2 |
| Peptide/Conjuagate | Conjugate |
| Technique | Cryo - TEM (Transmission Electron Microscopy) |
| Solvent | Water |
| Method | C16-βAH dissolved in Milli-Q water to the desired concentration and mixed using a vortex mixer, followed by sonication in an ultrasonic bath at ∼50 °C for 5−10 min. |
| Conc | 1 %wt |
| Temperature | 6.5 - 1.5 |
| Temperature | 50°C |
| Incubation Time | 5 - 10 minutes |
| Year | 2012 |
| Self assembly | Yes |
| Type of Self assembly | Thick Tapes and thin twisted fibers |
| Tertiary Structure (Technique) | Not Predicted), |
| Linear | |
| NA | |
| NA | |
| Nanofibers, Nanotape | |
| NA | |
| AH | |
| N.A. | |
| Primary information | |
| SAPdb ID | 1488, |
| PMID | 22788380 |
| Peptide Name | L-Carnosine |
| Peptide sequence | βAH |
| N-Terminal Modification | Palmitic acid |
| C-Terminal Modification | Free |
| Non-Terminal Modification | βA=beta-alanine |
| Length | 2 |
| Peptide/Conjuagate | Mixture |
| Conjugate partner | DPPC |
| Technique | Cryo - TEM (Transmission Electron Microscopy) |
| Solvent | Water |
| Method | C16-βAH dissolved in Milli-Q water to the desired concentration and mixed using a vortex mixer, followed by sonication in an ultrasonic bath at ∼50 °C for 5−10 min. |
| Conc | 0.03 wt % C16-βAH. 1.5 wt % DPPC solutions ( |
| Temperature | 6.5 - 1.5 |
| Temperature | 50°C |
| Incubation Time | 5 - 10 minutes |
| Year | 2012 |
| Self assembly | Yes |
| Type of Self assembly | Thick Tapes and vesicles |
| Tertiary Structure (Technique) | Not Predicted), |
| Linear | |
| NA | |
| NA | |
| Nanofibers, Nanotape | |
| 315 | |
| AH | |
| N.A. | |
| Primary information | |
| SAPdb ID | 1489, |
| PMID | 22788380 |
| Peptide Name | L-Carnosine |
| Peptide sequence | βAH |
| N-Terminal Modification | Palmitic acid |
| C-Terminal Modification | Free |
| Non-Terminal Modification | βA=beta-alanine |
| Length | 2 |
| Peptide/Conjuagate | Mixture |
| Conjugate partner | DPPC |
| Technique | Cryo - TEM (Transmission Electron Microscopy) |
| Solvent | Water |
| Method | A weighted amount of DPPC+C16-βAH was dissolved in ethanol in a 100 mL round-bottom flask. The ethanol was removed to form a thin DPPC film on the walls of the flask under reduced pressure using a rotary evaporator. Any residual solvent was removed under a stream of N2. A weighed amount of water was then added. The flask was then returned to the rotoevaporator, immersed in a water bath, and vigorously rotated for ∼5 min, to reconstitute the lipid film at 50 °C. The solution was thenput in a flask and vortexed at 50 °C for an additional 5 min |
| Conc | 1 %wt |
| Temperature | 6.5 - 1.5 |
| Temperature | 50°C |
| Incubation Time | 5 - 10 minutes |
| Year | 2012 |
| Self assembly | Yes |
| Type of Self assembly | Vesicles |
| Tertiary Structure (Technique) | Not Predicted), |
| Linear | |
| NA | |
| NA | |
| Nanovesicle | |
| 3635 | |
| AH | |
| N.A. | |
| Primary information | |
| SAPdb ID | 1548, |
| PMID | 21338121 |
| Peptide Name | L-carnosine |
| Peptide sequence | βAH |
| N-Terminal Modification | Fmoc(fluorenylmethoxycarbonyl) |
| C-Terminal Modification | Free |
| Non-Terminal Modification | βA=beta-alanine |
| Length | 2 |
| Peptide/Conjuagate | Peptide |
| Conjugate partner | None |
| Technique | Cryo - TEM (Transmission Electron Microscopy) |
| Solvent | Water |
| Method | Fmoc- βAH solutions and gels were dissolved in Milli-Q water by sonication in an ultrasonic bath at 35-40 C for 5-10 min. Upon cooling to room temperature, samples were allowed to stand for over three hours. Gelation was verified by tube inversion. |
| Conc | 1 wt% |
| Temperature | Room temperature |
| Incubation Time | 3 hours |
| Year | 2011 |
| Self assembly | Yes |
| Type of Self assembly | Fibrillar structure |
| Tertiary Structure (Technique) | Not Predicted), |
| Linear | |
| NA | |
| Stable upon drying | |
| Nanofibers | |
| 15 | |
| AH | |
| N.A. | |