Aim & Scope:
OSDDChemDesign is a web-based platform providing access to the compounds along with details on compound structures, properties, source and scientist who contributed the same. Specific details may be seen here.
In addition to chemical data, the platform is also customized to capture biological screening data, which includes whole cell based assays (M. smegmatis and M. tuberculosis), target based assay and cytotoxicity assays. For each assay performed, an assay ID has been assigned. The Community can provide additional assays, if they have followed a different protocol for screening and in such cases new assay IDs will be generated. The details on the screening protocols may be explored here. The entire data in OSDDChemDesign may be browsed for Identifiers, Classification Data, Biological Screening, Physicochemical Properties, Data Source, Record with Full Details.
OSDD has a strong team of synthetic and medicinal chemists pan India. Over past two years, the OSDD Chemistry Community has synthesized a large number of compounds. These compounds are designed with the objective of identifying novel scaffolds with anti-TB properties. It was imperative to set up a synthesis-screening system that facilitates the understanding of biological activity of these synthesized compounds to identify potential hits and iteratively enhance their efficacy and drug-like properties. As of now, more than 80 synthetic chemists are involved in synthesis of different classes of chemical compounds. These efforts are complemented by different screening platforms both in academia and as services from CROs, which are set up as open screening facility by OSDD.
The synthesis of compounds as well as screening takes places across several geographically distributed locations. Therefore, it is essential to set up a central repository for storing of compounds, the information associated with these compounds along with biological screening data.
Frequently Asked Question (Registration & LogIn related)
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How to Register to get Screen name & Password for OSDDChemDesign Login ?
Ans. Please follow the link: Click Here
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Forgot Password ?
Ans. Please follow the link: Click Here
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Problem proposing / uploading molecules ?
Ans. Please contact at: info@osdd.net (with OSDDChemDesign in Subject of Email)
Frequently Asked Questions (Compound Submission Related)
Q.1. How to submit data using Microsoft Excel file ?
Ans. Use this link:
Click