Details of CPPsite entry with Sequence CGGGYGRKKRRQRRR |
| Primary information | |
|---|---|
| PEPTIDE SEQUENCE | CGGGYGRKKRRQRRR |
| CPPsite ID | 2718, |
| PEPTIDE NAME | AgNP-TAT |
| CHIRALITY | L |
| LINEAR/CYCLIC | Linear |
| SOURCE | Protein derived |
| CATEGORY | Cationic |
| UPTAKE EFFICIENCY | AgNP-TAT showed significant enhancement in killing tumor cells, e.g. up to 24 fold higher compared to its counterpart without TAT-modification |
| PROPOSED UPTAKE MECHANISM | phagocytosis or a passive, nonspecific diffusion pathway through the cell membrane |
| INVITRO/INVIVO | In vitro and in vivo |
| CELL LINE | Caco-2 cells |
| In VIVO MODEL | Female nude mice having B16 melanoma |
| CARGO | Nanosilver Nanoparticles |
| PMID | 22682937 |
| PATENT | Unknown |
| Tertiary Structure (Technique) | 2718 (PEPstrMOD), |