Welcome to Sequence Card of Peptide


Details of CPPsite entry with Sequence FFLIPKGRRRRRRRRGC
Primary information
PEPTIDE SEQUENCEFFLIPKGRRRRRRRRGC
CPPsite ID 2690, 2703, 2706,
PEPTIDE NAMEPasR8 (Alexa), PasR8-p27kip1C, PasR8-PAD
CHIRALITYL, L, L
LINEAR/CYCLICLinear, Linear, Linear
SOURCESynthetic, Synthetic, Synthetic
CATEGORYCationic, Cationic, Cationic
SUB CELLULAR LOCALIZATIONCytosol, Cytosol, Cytosol
N-TERMINAL MODIFICATIONNA, NA, NA
C-TERMINAL MODIFICATIONAmidation, Amidation, Amidation
CHEMICAL MODIFICATIONNA, NA, NA
UPTAKE EFFICIENCYPasR8(Alexa) efficiently internalizes into cells a few minutes after peptide administration, NA, NA
PROPOSED UPTAKE MECHANISMMacropinocytosis, NA, NA
INVITRO/INVIVOIn vitro, In vitro, In vitro
CELL LINEHeLa, T98G glioma cells, HeLa, T98G glioma cells, HeLa, T98G glioma cells
In VIVO MODELNA, NA, NA
CARGOFluorophore (Alexa), Peptide (cyclin-dependent kinase inhibitor), Peptide [(Proapoptotic domain (PAD)]
PMID22486588, 22486588, 22486588
PATENTUnknown, Unknown, Unknown
Tertiary Structure
(Technique)		2690 (PEPstrMOD), 2703 (PEPstrMOD), 2706 (PEPstrMOD),