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Details of CPPsite entry with Sequence KKLFKKILKKL
Primary information
PEPTIDE SEQUENCEKKLFKKILKKL
CPPsite ID 2337, 2339,
PEPTIDE NAMECF-BP16, BP326
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCESynthetic, Synthetic
CATEGORYCationic, Cationic
SUB CELLULAR LOCALIZATIONCytoplasm, Cytoplasm
N-TERMINAL MODIFICATIONFree, Free
C-TERMINAL MODIFICATIONAmidation, Amidation
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYHigh (compare to Tat), High (similar to that of CF-BP16)
PROPOSED UPTAKE MECHANISMClathrin dependent endocytosis, NA
INVITRO/INVIVOIn vitro, In vitro
CELL LINEMCF-7, CAPAN-1 and mouse embryonic fibroblast 3T3, MCF-7, CAPAN-1 and mouse embryonic fibroblast 3T3
In VIVO MODELNA, NA
CARGOFluorophore [5(6)-carboxyfluorescein (CF)], Fluorophore [5(6)-carboxyfluorescein (CF)], CLB
PMID24480922, 24480922
PATENTUnknown, Unknown
Tertiary Structure
(Technique)
2337 (PEPstrMOD), 2339 (PEPstrMOD),